Norgenotech publications from PubMed

1. PMID: 40382189
New Approach Methods (NAMs) for genotoxicity assessment of nano- and advanced materials; Advantages and challenges.
Gutleb AC, Murugadoss S, Stępnik M, SenGupta T, El Yamani N, Longhin EM, Olsen AH, Wyrzykowska E, Jagiello K, Judzinska B, Cambier S, Honza T, McFadden E, Shaposhnikov S, Puzyn T, Serchi T, Weber P, Arnesdotter E, Skakalova V, Jirsova K, Grudzinski IP, Collins A, Rundén-Pran E, Dusinska M.Mutat Res Genet Toxicol Environ Mutagen. 2025 May-Jun;904:503867. doi: 10.1016/j.mrgentox.2025.503867. Epub 2025 Mar 30.PMID: 40382189 Review.

2. PMID: 40219078
SL-6 Mimic Is a Biostimulant for Chlorella sorokiniana and Enhances the Plant Biostimulant Effect of Microalgal Extract.
Popa DG, Tritean N, Georgescu F, Lupu C, Shaposhnikov S, Constantinescu-Aruxandei D, Oancea F.Plants (Basel). 2025 Mar 24;14(7):1010. doi: 10.3390/plants14071010.PMID: 40219078 Free PMC article.

3. PMID: 40180023
Plant-based diet and oxidative stress-induced DNA damage in post-surgery colorectal cancer patients: Results from a randomized controlled trial.
Nordengen AL, Krutto A, Kværner AS, Alavi DT, Henriksen HB, Kolle Å, Henriksen C, Smeland S, Bøhn SK, Zheng C, Shaposhnikov S, Collins AR, Blomhoff R.Free Radic Biol Med. 2025 Jun;233:240-249. doi: 10.1016/j.freeradbiomed.2025.03.047. Epub 2025 Apr 1.PMID: 40180023 Free article. Clinical Trial.

4. PMID: 39963750
Slightly increased level of DNA migration in the comet assay: does statistical significance equal biological significance?
Møller P, Collins A, Rodriguez-Garraus A, Langie SAS, Godschalk R, Azqueta A.Mutagenesis. 2025 Apr 24;40(2):99-110. doi: 10.1093/mutage/geaf004.PMID: 39963750 Free PMC article. Review.

5. PMID: 39872495
CompSafeNano project: NanoInformatics approaches for safe-by-design nanomaterials.
Zouraris D, Mavrogiorgis A, Tsoumanis A, Saarimäki LA, Del Giudice G, Federico A, Serra A, Greco D, Rouse I, Subbotina J, Lobaskin V, Jagiello K, Ciura K, Judzinska B, Mikolajczyk A, Sosnowska A, Puzyn T, Gulumian M, Wepener V, Martinez DST, Petry R, El Yamani N, Rundén-Pran E, Murugadoss S, Shaposhnikov S, Minadakis V, Tsiros P, Sarimveis H, Longhin EM, SenGupta T, Olsen AH, Skakalova V, Hutar P, Dusinska M, Papadiamantis AG, Gheorghe LC, Reilly K, Brun E, Ullah S, Cambier S, Serchi T, Tämm K, Lorusso C, Dondero F, Melagrakis E, Fraz MM, Melagraki G, Lynch I, Afantitis A.Comput Struct Biotechnol J. 2024 Dec 25;29:13-28. doi: 10.1016/j.csbj.2024.12.024. eCollection 2025.PMID: 39872495 Free PMC article.

6. PMID: 39725965
Hazard assessment of nanomaterials: how to meet the requirements for (next generation) risk assessment.
Longhin EM, Rios-Mondragon I, Mariussen E, Zheng C, Busquets M, Gajewicz-Skretna A, Hofshagen OB, Bastus NG, Puntes VF, Cimpan MR, Shaposhnikov S, Dusinska M, Rundén-Pran E.Part Fibre Toxicol. 2024 Dec 27;21(1):54. doi: 10.1186/s12989-024-00615-4.PMID: 39725965 Free PMC article.

7. PMID: 39683277
Toward Standardization of a Lung New Approach Model for Toxicity Testing of Nanomaterials.
Elje E, Camassa LMA, Shaposhnikov S, Anmarkrud KH, Skare Ø, Nilsen AM, Zienolddiny-Narui S, Rundén-Pran E.Nanomaterials (Basel). 2024 Nov 24;14(23):1888. doi: 10.3390/nano14231888.PMID: 39683277 Free PMC article.

8. PMID: 39670868
A pooled analysis of host factors that affect nucleotide excision repair in humans.
Zheng C, Shaposhnikov S, Collins A, Brunborg G, Azqueta A, Langie SAS, Dusinska M, Slyskova J, Vodicka P, van Schooten FJ, Bonassi S, Milic M, Orlow I, Godschalk R.Mutagenesis. 2025 Apr 24;40(2):137-144. doi: 10.1093/mutage/geae028.PMID: 39670868 Free PMC article.

9. PMID: 38869318
Surface-Bioengineered Extracellular Vesicles Seeking Molecular Biotargets in Lung Cancer Cells.
Kowalczyk A, Dziubak D, Kasprzak A, Sobczak K, Ruzycka-Ayoush M, Bamburowicz-Klimkowska M, Sęk S, Rios-Mondragon I, Żołek T, Runden-Pran E, Shaposhnikov S, Cimpan MR, Dusinska M, Grudzinski IP, Nowicka AM.ACS Appl Mater Interfaces. 2024 Jun 26;16(25):31997-32016. doi: 10.1021/acsami.4c04265. Epub 2024 Jun 13.PMID: 38869318 Free PMC article.

10. PMID: 38801838
Lack of cytotoxic and genotoxic effects of mPEG-silane coated iron(III) oxide nanoparticles doped with magnesium despite cellular uptake in cancerous and noncancerous lung cells.
Sikorska M, Ruzycka-Ayoush M, Rios-Mondragon I, Longhin EM, Meczynska-Wielgosz S, Wojewodzka M, Kowalczyk A, Kasprzak A, Nowakowska J, Sobczak K, Muszynska M, Cimpan MR, Runden-Pran E, Shaposhnikov S, Kruszewski M, Dusinska M, Nowicka AM, Grudzinski IP.Toxicol In Vitro. 2024 Aug;99:105850. doi: 10.1016/j.tiv.2024.105850. Epub 2024 May 25.PMID: 38801838

11. PMID: 38762060
Attenuation of DNA base oxidation in post-surgery colorectal stage III patients at subsequent follow-ups.
Nordengen AL, Krutto A, Kværner AS, Alavi DT, Henriksen HB, Smeland S, Paur I, Zheng C, Shaposhnikov S, Collins AR, Blomhoff R.Free Radic Biol Med. 2024 Aug 20;221:75-80. doi: 10.1016/j.freeradbiomed.2024.05.029. Epub 2024 May 16.PMID: 38762060 Free article. Clinical Trial.

12. PMID: 38588903
Effect of a personalized intensive dietary intervention on base excision repair (BER) in colorectal cancer patients: Results from a randomized controlled trial.
Nordengen AL, Zheng C, Krutto A, Kværner AS, Alavi DT, Henriksen HB, Henriksen C, Smeland S, Bøhn SK, Paur I, Shaposhnikov S, Collins AR, Blomhoff R.Free Radic Biol Med. 2024 Jun;218:178-189. doi: 10.1016/j.freeradbiomed.2024.04.211. Epub 2024 Apr 6.PMID: 38588903 Free article. Clinical Trial.

13. PMID: 38575250
In memory of Dr. Ir. Gudrun Koppen (1969-2024).
Collins AR, Azqueta A, Schoeters G, Slingers G, Dusinska M, Langie SAS; Gudrun’s scientist collaborators, colleagues and friends.Mutat Res Genet Toxicol Environ Mutagen. 2024 Apr;895:503751. doi: 10.1016/j.mrgentox.2024.503751. Epub 2024 Mar 19.PMID: 38575250 No abstract available.

14. PMID: 38537480
An ecotoxicological assessment of a strigolactone mimic used as the active ingredient in a plant biostimulant formulation.
Brooks SJ, Gomes T, Almeida AC, Christou M, Zheng C, Shaposhnikov S, Popa DG, Georgescu F, Oancea F.Ecotoxicol Environ Saf. 2024 Apr 15;275:116244. doi: 10.1016/j.ecoenv.2024.116244. Epub 2024 Mar 26.PMID: 38537480 Free article.

15. PMID: 38141887
DNA base oxidation in relation to TNM stages and chemotherapy treatment in colorectal cancer patients 2-9 months post-surgery.
Nordengen AL, Kværner AS, Krutto A, Alavi DT, Henriksen HB, Henriksen C, Raastad T, Smeland S, Bøhn SK, Shaposhnikov S, Collins AR, Blomhoff R.Free Radic Biol Med. 2024 Feb 20;212:174-185. doi: 10.1016/j.freeradbiomed.2023.12.016. Epub 2023 Dec 22.PMID: 38141887 Free article.

16. PMID: 37357815
Long-term cryopreservation of potassium bromate positive assay controls for measurement of oxidatively damaged DNA by the Fpg-modified comet assay: results from the hCOMET ring trial.
Møller P, Azqueta A, Rodriguez-Garraus A, Bakuradze T, Richling E, Bankoglu EE, Stopper H, Claudino Bastos V, Langie SAS, Jensen A, Ristori S, Scavone F, Giovannelli L, Wojewódzka M, Kruszewski M, Valdiglesias V, Laffon B, Costa C, Costa S, Paulo Teixeira J, Marino M, Del Bo’ C, Riso P, Zheng C, Shaposhnikov S, Collins A.Mutagenesis. 2023 Oct 14;38(5):264-272. doi: 10.1093/mutage/gead020.PMID: 37357815

17. PMID: 37357800
DNA strand break levels in cryopreserved mononuclear blood cell lines measured by the alkaline comet assay: results from the hCOMET ring trial.
Møller P, Azqueta A, Rodriguez-Garraus A, Bakuradze T, Richling E, Bankoglu EE, Stopper H, Claudino Bastos V, Langie SAS, Jensen A, Ristori S, Scavone F, Giovannelli L, Wojewódzka M, Kruszewski M, Valdiglesias V, Laffon B, Costa C, Costa S, Paulo Teixeira J, Marino M, Del Bo C, Riso P, Zheng C, Shaposhnikov S, Collins A.Mutagenesis. 2023 Oct 14;38(5):273-282. doi: 10.1093/mutage/gead019.PMID: 37357800

18. PMID: 37349528
Comparison of comet-based approaches to assess base excision repair.
Zheng C, Shaposhnikov S, Collins A, Brunborg G, Oancea F, Van Schooten FJ, Godschalk R.Arch Toxicol. 2023 Aug;97(8):2273-2281. doi: 10.1007/s00204-023-03543-y. Epub 2023 Jun 22.PMID: 37349528 Free PMC article.

19. PMID: 37233347
Visual comet scoring revisited: a guide to scoring comet assay slides and obtaining reliable results.
Møller P, Azqueta A, Sanz-Serrano J, Bakuradze T, Richling E, Eyluel Bankoglu E, Stopper H, Claudino Bastos V, Langie SAS, Jensen A, Scavone F, Giovannelli L, Wojewódzka M, Kruszewski M, Valdiglesias V, Laffon B, Costa C, Costa S, Teixeira JP, Marino M, Del Bo C, Riso P, Zheng C, Shaposhnikov S, Collins A.Mutagenesis. 2023 Oct 14;38(5):253-263. doi: 10.1093/mutage/gead015.PMID: 37233347

20. PMID: 37228081
Inter-laboratory variation in measurement of DNA damage by the alkaline comet assay in the hCOMET ring trial.
Møller P, Azqueta A, Collia M, Bakuradze T, Richling E, Bankoglu EE, Stopper H, Bastos VC, Langie SAS, Jensen A, Ristori S, Scavone F, Giovannelli L, Wojewódzka M, Kruszewski M, Valdiglesias V, Laffon B, Costa C, Costa S, Teixeira JP, Marino M, Del Bo C, Riso P, Zheng C, Shaposhnikov S, Collins A.Mutagenesis. 2023 Oct 14;38(5):283-294. doi: 10.1093/mutage/gead014.PMID: 37228081

21. PMID: 36932276
Assay conditions for estimating differences in base excision repair activity with Fpg-modified comet assay.
Zheng C, Collins A, Brunborg G, van Schooten FJ, Nordengen AL, Shaposhnikov S, Godschalk R.Cell Biol Toxicol. 2023 Dec;39(6):2775-2786. doi: 10.1007/s10565-023-09801-0. Epub 2023 Mar 17.PMID: 36932276 Free PMC article.

22. PMID: 36707722
Measuring DNA modifications with the comet assay: a compendium of protocols.
Collins A, Møller P, Gajski G, Vodenková S, Abdulwahed A, Anderson D, Bankoglu EE, Bonassi S, Boutet-Robinet E, Brunborg G, Chao C, Cooke MS, Costa C, Costa S, Dhawan A, de Lapuente J, Bo’ CD, Dubus J, Dusinska M, Duthie SJ, Yamani NE, Engelward B, Gaivão I, Giovannelli L, Godschalk R, Guilherme S, Gutzkow KB, Habas K, Hernández A, Herrero O, Isidori M, Jha AN, Knasmüller S, Kooter IM, Koppen G, Kruszewski M, Ladeira C, Laffon B, Larramendy M, Hégarat LL, Lewies A, Lewinska A, Liwszyc GE, de Cerain AL, Manjanatha M, Marcos R, Milić M, de Andrade VM, Moretti M, Muruzabal D, Novak M, Oliveira R, Olsen AK, Owiti N, Pacheco M, Pandey AK, Pfuhler S, Pourrut B, Reisinger K, Rojas E, Rundén-Pran E, Sanz-Serrano J, Shaposhnikov S, Sipinen V, Smeets K, Stopper H, Teixeira JP, Valdiglesias V, Valverde M, van Acker F, van Schooten FJ, Vasquez M, Wentzel JF, Wnuk M, Wouters A, Žegura B, Zikmund T, Langie SAS, Azqueta A.Nat Protoc. 2023 Mar;18(3):929-989. doi: 10.1038/s41596-022-00754-y. Epub 2023 Jan 27.PMID: 36707722 Free PMC article. Review.

23. PMID: 36669811
Calibration of the comet assay using ionising radiation.
Brunborg G, Eide DM, Graupner A, Gutzkow K, Shaposhnikov S, Kruszewski M, Sirota N, Jones GDD, Koppen G, Vanhavere F, Møller P, Stetina R, Dahl H, Collins A.Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.PMID: 36669811 Free article.

24. PMID: 35091237
Decitabine potentiates efficacy of doxorubicin in a preclinical trastuzumab-resistant HER2-positive breast cancer models.
Buocikova V, Longhin EM, Pilalis E, Mastrokalou C, Miklikova S, Cihova M, Poturnayova A, Mackova K, Babelova A, Trnkova L, El Yamani N, Zheng C, Rios-Mondragon I, Labudova M, Csaderova L, Kuracinova KM, Makovicky P, Kucerova L, Matuskova M, Cimpan MR, Dusinska M, Babal P, Chatziioannou A, Gabelova A, Rundén-Pran E, Smolkova B.Biomed Pharmacother. 2022 Mar;147:112662. doi: 10.1016/j.biopha.2022.112662. Epub 2022 Jan 25.PMID: 35091237 Free article.

25. PMID: 32319518
Potassium bromate as positive assay control for the Fpg-modified comet assay.
Møller P, Muruzabal D, Bakuradze T, Richling E, Bankoglu EE, Stopper H, Langie SAS, Azqueta A, Jensen A, Scavone F, Giovannelli L, Wojewódzka M, Kruszewski M, Valdiglesias V, Laffon B, Costa C, Costa S, Teixeira JP, Marino M, Del Bo’ C, Riso P, Shaposhnikov S, Collins A.Mutagenesis. 2020 Sep 12;35(4):341-348. doi: 10.1093/mutage/geaa011.PMID: 32319518

26. PMID: 31421733
Isolation of leukocytes from frozen buffy coat for comet assay analysis of DNA damage.
Bøhn SK, Vebraite V, Shaposhnikov S, Collins AR.Mutat Res Genet Toxicol Environ Mutagen. 2019 Jul;843:18-23. doi: 10.1016/j.mrgentox.2019.03.010. Epub 2019 Mar 31.PMID: 31421733

27. PMID: 31013686
Prevention of Deficit in Neuropsychiatric Disorders through Monitoring of Arsenic and Its Derivatives as Well as Through Bioinformatics and Cheminformatics.
Avram S, Udrea AM, Negrea A, Ciopec M, Duteanu N, Postolache C, Duda-Seiman C, Duda-Seiman D, Shaposhnikov S.Int J Mol Sci. 2019 Apr 12;20(8):1804. doi: 10.3390/ijms20081804.PMID: 31013686 Free PMC article. Review.

28. PMID: 30910685
Methamphetamine (“crystal meth”) causes induction of DNA damage and chromosomal aberrations in human derived cells.
Ropek N, Al-Serori H, Mišík M, Nersesyan A, Sitte HH, Collins AR, Shaposhnikov S, Knasmüller S, Kundi M, Ferk F.Food Chem Toxicol. 2019 Jun;128:1-7. doi: 10.1016/j.fct.2019.03.035. Epub 2019 Mar 22.PMID: 30910685

29. PMID: 30448878
Consumption of a dark roast coffee blend reduces DNA damage in humans: results from a 4-week randomised controlled study.
Schipp D, Tulinska J, Sustrova M, Liskova A, Spustova V, Lehotska Mikusova M, Krivosikova Z, Rausova K, Collins A, Vebraite V, Volkovova K, Rollerova E, Barancokova M, Shaposhnikov S.Eur J Nutr. 2019 Dec;58(8):3199-3206. doi: 10.1007/s00394-018-1863-2. Epub 2018 Nov 17.PMID: 30448878 Clinical Trial.

30. PMID: 29350075
Characterization of the proteome and lipidome profiles of human lung cells after low dose and chronic exposure to multiwalled carbon nanotubes.
Phuyal S, Kasem M, Knittelfelder O, Sharma A, Fonseca DM, Vebraite V, Shaposhnikov S, Slupphaug G, Skaug V, Zienolddiny S.Nanotoxicology. 2018 Mar;12(2):138-152. doi: 10.1080/17435390.2018.1425500. Epub 2018 Jan 19.PMID: 29350075 Free article.

31. PMID: 29113734
Cellular responses of human astrocytoma cells to dust from the Acheson process: An in vitro study.
Arnoldussen YJ, Ervik TK, Berlinger B, Kero I, Shaposhnikov S, Zienolddiny S.Neurotoxicology. 2018 Mar;65:241-247. doi: 10.1016/j.neuro.2017.11.001. Epub 2017 Nov 4.PMID: 29113734 Free article.

32. PMID: 28973009
TLR9 stimulation of B-cells induces transcription of p53 and prevents spontaneous and irradiation-induced cell death independent of DNA damage responses. Implications for Common variable immunodeficiency.
Holm KL, Syljuåsen RG, Hasvold G, Alsøe L, Nilsen H, Ivanauskiene K, Collas P, Shaposhnikov S, Collins A, Indrevær RL, Aukrust P, Fevang B, Blomhoff HK.PLoS One. 2017 Oct 3;12(10):e0185708. doi: 10.1371/journal.pone.0185708. eCollection 2017.PMID: 28973009 Free PMC article.

33. PMID: 28710764
Twelve-Gel Comet Assay Format for Quick Examination of DNA Damage and Repair.
Shaposhnikov S, Collins A.Methods Mol Biol. 2017;1644:181-186. doi: 10.1007/978-1-4939-7187-9_16.PMID: 28710764

34. PMID: 28161308
Sensitive detection of DNA oxidation damage induced by nanomaterials.
Collins A, El Yamani N, Dusinska M.Free Radic Biol Med. 2017 Jun;107:69-76. doi: 10.1016/j.freeradbiomed.2017.02.001. Epub 2017 Feb 2.PMID: 28161308 Review.

35. PMID: 27858150
Coffee and oxidative stress: a human intervention study.
Shaposhnikov S, Hatzold T, Yamani NE, Stavro PM, Lorenzo Y, Dusinska M, Reus A, Pasman W, Collins A.Eur J Nutr. 2018 Mar;57(2):533-544. doi: 10.1007/s00394-016-1336-4. Epub 2016 Nov 17.PMID: 27858150 Clinical Trial.

36. PMID: 27321801
Active biomonitoring of mussels Mytilus galloprovincialis with integrated use of micronucleus assay and physiological indices to assess harbor pollution.
Gherras Touahri H, Boutiba Z, Benguedda W, Shaposhnikov S.Mar Pollut Bull. 2016 Sep 15;110(1):52-64. doi: 10.1016/j.marpolbul.2016.06.029. Epub 2016 Jun 16.PMID: 27321801 Review.

37. PMID: 25827891
Fluorescent in situ hybridization on comets: FISH comet.
Shaposhnikov S, El Yamani N, Collins AR.Methods Mol Biol. 2015;1288:363-73. doi: 10.1007/978-1-4939-2474-5_21.PMID: 25827891

38. PMID: 25389434
High throughput sample processing and automated scoring.
Brunborg G, Jackson P, Shaposhnikov S, Dahl H, Azqueta A, Collins AR, Gutzkow KB.Front Genet. 2014 Oct 28;5:373. doi: 10.3389/fgene.2014.00373. eCollection 2014.PMID: 25389434 Free PMC article. Review.

39. PMID: 24955366
Chondroitin sulfate proteoglycans: structure-function relationship with implication in neural development and brain disorders.
Avram S, Shaposhnikov S, Buiu C, Mernea M.Biomed Res Int. 2014;2014:642798. doi: 10.1155/2014/642798. Epub 2014 May 14.PMID: 24955366 Free PMC article. Review.